Glycomet: Advanced Glycemic Control for Type 2 Diabetes

Glycomet
| Product dosage: 500mg | |||
|---|---|---|---|
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| 270 | $0.21 | $64.50 $57.00 (12%) | 🛒 Add to cart |
| 360 | $0.20
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Glycomet is a widely prescribed oral antidiabetic medication containing metformin hydrochloride, designed to help manage blood glucose levels in adults with type 2 diabetes. As a first-line therapy, it works by reducing hepatic glucose production and improving insulin sensitivity in peripheral tissues. When combined with diet and exercise, Glycomet supports sustainable metabolic health and reduces the risk of diabetes-related complications. Trusted by healthcare professionals globally, it offers a balance of efficacy and safety for long-term glycemic management.
Features
- Contains metformin hydrochloride as the active ingredient
- Available in various strengths: 500 mg, 850 mg, and 1000 mg tablets
- Film-coated for easier swallowing and reduced gastrointestinal irritation
- Manufactured under strict pharmaceutical quality standards
- Often prescribed as monotherapy or in combination with other antidiabetic agents
Benefits
- Effectively lowers fasting and postprandial blood glucose levels
- Reduces HbA1c by an average of 1–2%, supporting long-term glycemic targets
- Associated with weight neutrality or modest weight loss, unlike some other antidiabetic drugs
- May improve lipid profiles and offer cardiovascular protective benefits
- Low risk of hypoglycemia when used as monotherapy
- Cost-effective and widely accessible treatment option
Common use
Glycomet is primarily indicated for the management of type 2 diabetes mellitus in adults. It is used when glycemic control cannot be achieved through diet and exercise alone. It may also be prescribed for off-label uses such as polycystic ovary syndrome (PCOS) or prediabetes under specialist supervision, though these are not its primary indications.
Dosage and direction
The typical starting dose for Glycomet is 500 mg once or twice daily, or 850 mg once daily, taken with meals to minimize gastrointestinal side effects. Dosage may be gradually increased at intervals of one to two weeks based on glycemic response and tolerance, up to a maximum of 2550 mg per day divided into two or three doses. Extended-release formulations should be taken once daily with the evening meal. Always follow the specific instructions provided by the prescribing healthcare professional.
Precautions
- Renal function should be assessed before initiation and periodically during treatment.
- Avoid use in conditions predisposing to renal impairment or hypoxia (e.g., dehydration, acute congestive heart failure).
- Temporarily discontinue prior to iodinated contrast imaging procedures and major surgery.
- Monitor for signs of lactic acidosis, though rare.
- Vitamin B12 levels should be monitored periodically with long-term use.
Contraindications
- Hypersensitivity to metformin or any component of the formulation.
- Severe renal impairment (eGFR <30 mL/min/1.73m²).
- Acute or chronic metabolic acidosis, including diabetic ketoacidosis.
- History of lactic acidosis.
- Acute conditions such as dehydration, severe infection, or shock.
Possible side effects
Common side effects may include:
- Gastrointestinal disturbances: nausea, vomiting, diarrhea, abdominal discomfort, and metallic taste
- These often subside with continued use or dose adjustment
Less common but serious side effects:
- Lactic acidosis (symptoms include malaise, myalgia, respiratory distress, abdominal pain)
- Vitamin B12 deficiency with prolonged use
- Hypoglycemia, especially when used with other glucose-lowering agents
Drug interaction
- Cationic drugs (e.g., cimetidine, ranitidine) may compete for renal tubular secretion and increase metformin levels.
- Alcohol consumption increases the risk of lactic acidosis.
- Drugs that affect renal function (e.g., diuretics, NSAIDs) may alter metformin excretion.
- Hypoglycemic agents like sulfonylureas or insulin may enhance glucose-lowering effects.
Missed dose
If a dose is missed, take it as soon as remembered unless it is almost time for the next dose. Do not double the dose to make up for a missed one. Resume the regular dosing schedule.
Overdose
Overdose may lead to hypoglycemia or lactic acidosis. Symptoms of hypoglycemia include sweating, trembling, blurred vision, and confusion. Lactic acidosis may present with vomiting, abdominal pain, and hyperventilation. Seek immediate medical attention. Hypoglycemia should be treated with oral glucose or intravenous dextrose.
Storage
Store at room temperature (15–30°C) in a dry place, protected from light and moisture. Keep out of reach of children. Do not use after the expiration date printed on the packaging.
Disclaimer
This information is for educational purposes and does not replace professional medical advice. Always consult a healthcare provider for diagnosis, treatment decisions, and personalized dosage recommendations. Do not initiate or discontinue medication without medical supervision.
Reviews
Glycomet is highly regarded in clinical practice for its efficacy, safety profile, and role as a foundational therapy in type 2 diabetes management. Many patients report improved glycemic control with minimal side effects after the initial adjustment period. Healthcare professionals appreciate its versatility in combination regimens and its favorable effects on weight and cardiovascular risk factors.


